Slitterhead: Jar Of Poison RE (2nd Loop) Walkthrough

Slitterhead's RE missions continue to be some of its best offerings, with Jar of Poison RE (2nd Loop) allowing you to uncover more mysterious things about the cult and its facility. While the first visit to the facility ended in chaos, do not underestimate just how much more south everything can truly go.

Overall, while this mission follows the same ebbs and flows as others, it's eerie and creepy and delivers on its atmosphere to make it one of our favorites in the game. Even if the boss encounters aren't anything we haven't seen or defeated already but, hey, we'll take it at this point!

Starting Jar Of Poison RE (2nd Loop) In Slitterhead

Since there are no locked characters for the Jar of Poison RE (2nd Loop) mission in Slitterhead, you can choose whichever two Rarities you'd like, allowing you to go in with your best ones. For us, we chose Edo and Julee to clear the mission with, as we love their Burning Edge and Revive All Skills.

Pretty much any character will be fine for this mission, so choose whoever you're most comfortable with. We do recommend having at least Edo or Julee as your companion, but it's not a make-or-break situation. Their Skills are just extremely potent and can carry you quite a lot!

Gather Information On Yin Yue

Your first objective is quite simple: Gather information on Yin Yue from the nearby Followers. Head out of the kitchen and speak to the man just outside of the doorway. From here, turn right and talk to the couple in the hallway. After talking with them, you will learn that he went to visit the Master in the depths of the facility.

Go To Master's Room

Turn left from the couple and head down the hallway, making your way to the staircase that leads to the first floor and following them all the way down. Once here, follow the hallway out until you see the laundry room on your left, with lots of blood pooled up on the floor.

Enter the laundry room and head left. You will find an open door and a trail of blood leading further inside. Follow the trail of blood and jump down into the depths of the facility to find a bloodied and battered body lying on the ground. Inspect the body, then continue pushing even further into the underbelly of the facility.

Investigate The Room

From the body at the base of the facility, follow the pathway through the winding hallways to reach the Master's Room, where you will find three bodies strewn across the floor. Examine all of them first, then examine the mummified corpse of the Master to proceed forward with the mission.

You don't technically have to examine all the bodies, but you will glean some interesting information by doing so, so we highly recommend it. If you just want to move the mission along, interacting with the Master's mummified corpse will be enough.

Follow The Blood Trail

Continue following the blood trail out of the Master's Room and into the cave system to encounter a small group of little Slitterheads. Quickly dispatch them and continue pushing further into the cave to run into a lesser Slitterhead. Make quick work of it and press onward.

Another group of little Slitterheads will ambush you in a large room. While they are annoying and seemingly never stop coming, you can eliminate them easily with just a single hit from your basic attack. After dealing with them, push slightly forward to encounter even more little Slitterheads and a few lesser Slitterheads. Deal with them as you did the others and move on.

Keep following the pathway and head up the staircase to enter the facility's basement again to see Yin Yue standing beside a Slitterhead that's drinking from a vat of blood, triggering a cutscene.

Defeat Slitterheads

After the brief cutscene, you will be thrown into an encounter with the Slitterhead, who was drinking from the vat of blood. Activate Burning Edge and quickly unleash a flurry of Angel Steps onto it to eliminate it quickly and efficiently, summoning another wave of Slitterheads forward.

There will be one standard Slitterhead and a few lesser ones, allowing you to handle it relatively effortlessly, especially if you brought Julee along for the mission. Activate Revive All if things get hairy, then use Burning Edge again to clean things up. If you chose Alex as one of your Rarities, his Blood Well and Bloody Blast combo will also be perfect here!

Go To The Residential Area

Head through the door and follow the pathway further into the basement of the facility to find two normal Slitterheads. Use Burning Edge and Angel Step to make quick work of them, then continue up the stairs to find three lesser Slitterheads. Take them out swiftly with your Blood Weapon.

Next, follow the hallway to another staircase and take it up to another narrow hallway that leads to a door. Go through the door to reach the kitchen of the Residential Area of the facility, triggering a cutscene with Tommy and other Followers, ultimately leading to a boss fight.

Defeat Tommy - Warty Frogfish Slitterhead

With Tommy losing his mind and turning into the Warty Frogfish Slitterhead, you must deal with him before moving any further. You have faced this exact same Slitterhead several times already, and yes, it's the same now as it was before, so it shouldn't pose too much of a threat.

This Slitterhead has one attack you must keep your head on a swivel for, and that's its Sweep Attack, which cannot be guarded against or parried. This move is telegraphed by the Slitterhead flashing a bright red light, giving you the sign to run as far away from it as possible. Or simply switch to a Follower or your other Rarity that's far enough away to avoid taking damage.

Aside from that, you shouldn't struggle too much during this encounter. If you have Edo on your team, activating Burning Edge and utilizing his Angel Steps will demolish its health in mere seconds. We also strongly urge you to keep switching to nearby followers to get behind it to land attacks, as that will stun it faster!

Chase The Slitterhead

Taking Tommy down will have a woman turn into a Slitterhead from the sheer emotional trauma, having her flee the kitchen, forcing you to chase after her. She will run off into the courtyard of the facility, allowing you to simply jump into it from the second floor's balcony.

Additionally, you can take the stairway down to the first floor and exit through the side door, allowing you to explore the facility further to gather Memory Fragments or even tackle a Shrine. Whichever you choose to do, you will ultimately have to fight this Slitterhead, so be prepared.

Defeat Warty Frogfish Slitterhead

Nope, you didn't read that incorrectly. The final boss encounter of this mission is another Warty Frogfish Slitterhead. And, no, it doesn't offer anything different whatsoever, making it another easy encounter that you can bulldoze through with Edo's Burning Edge and Angel Step combo.

Julee can also use Edo's Burning Edge to make her deal even more damage than ever before, enabling her to stagger it extremely fast and then follow up with her Sonic Claws to keep applying nonstop pressure and damage. Overall, this encounter is not anything you haven't seen before or have already dealt with, which is unfortunate.

Deal with it the exact same way you finished the ones from previous missions or the one you fought mere minutes ago in the kitchen to complete the mission!

Jar Of Poison RE (2nd Loop) Rewards

Wrapping up Jar of Poison RE (2nd Loop) for the first time will grant you 24 Skill Tokens to level up any Blood Weapon, Active Skill, or Passive Skill for any Rarity you like. As you likely know by now, these Skill Tokens are shared between all Rarities, so don't waste them.

Lastly, you will unlock more 'Talk' options, so be sure to go through all of them to unlock more Missions and draw nearer to the game's conclusion!

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