Path Of Exile 2: Viper Napuatzi Boss Guide

This Path of Exile 2 guide details how to defeat Viper Napuatzi, a challenging Act 3 boss. Her high elemental resistances and chaos-based attacks make her a formidable opponent for leveling characters.

This guide covers her attacks, counter-strategies, and helpful tips. Note that Path of Exile 2 is in Early Access, so information may change.

Viper Napuatzi's Location

You'll find Viper Napuatzi in Utzaal during the "Legacy of the Vaal" quest, near the end of Act 3. Defeating her is mandatory to progress to Aggorat and The Black Chambers. Utzaal is Area Level 43, suggesting a player level around 50 is ideal. She's highly resistant to fire, cold, lightning, and physical damage; consider elemental penetration if not using chaos damage.

Preparation and Battle Strategies

Viper Napuatzi primarily uses chaos damage attacks. Mitigation options include:

• Chaos Inoculation: Passive skill tree node granting chaos immunity (requires energy shield investment).
• Quest Reward: Completing "The Slithering Dead" provides 10% permanent chaos resistance.
• Unique Items: Affordable options like Serpent's Egg, Oaksworn, Snakebite, and Ghostwrithe.
• Vendor Items: Check vendors for chaos resistance items (Amethyst Rings are a good base).
• Antidote Charm: Provides temporary poison immunity.

The fight occurs in a shrinking arena; aim for at least 20% movement speed for dodging. Flask charges often deplete; consider the "Gains # Charges Per Second" mod on your flasks. Prioritize quickly defeating her to minimize her attack spam. Melee characters generally find this fight harder than ranged characters. Endgame builds (Spark, Lightning Arrow, attribute stacking) can easily overcome her with sufficient chaos resistance. Skills like Tempest Bell and Frost Wall can help control her position. If chaos resistance is lacking, maximize HP to survive. Dodging is crucial; perfect timing is key to success.

Viper Napuatzi's Attacks

Viper Napuatzi uses two attack styles: Spear and Unarmed.

Spear Attacks:

electric projectiles that ricochet off walls.Avoid walls, dodge sideways.Melee ComboThree-hit melee combo ending in a poison cloud.Dodge backward twice, then roll.Forward DashDashes forward, spewing poison.Roll in any direction.

Attack	Description	How to Dodge
Spear Throw	Throws her spear, dealing poison damage.	Dodge in any direction.
Lightning Spear	Spear splits into

She switches to Unarmed attacks around 80% HP (and again near 10%).AttackDescriptionHow to DodgeMeteorsSummons exploding meteors dealing fire and chaos damage.Watch for ground indicators, avoid AoE.Slam AttackSlams the ground, creating a large AoE.Roll backward when she leaps.SnakesSummons roaming snakes dealing chaos damage.Stay away from walls to avoid ricochets.Poison DartsFires a barrage of poisonous projectiles, culminating in a cone-shaped attack.Keep moving.Spear ThrustSoldiers' spears glow before a thrusting attack.Dodge when spears glow green.

Pay attention to her dialogue; it often precedes certain attacks. After defeating her, defeat the remaining soldiers.

Loot

Viper Napuatzi drops random items and currency. After her defeat, proceed to Aggorat. Note that Cruel difficulty is only available in Early Access.

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