Warframe: Best Pathocyst Builds

Warframe's Infested arsenal includes some truly unique weapons. The Pathocyst, a Glaive, stands out by summoning a swarm of Infested maggots with each swing, offering crowd control rather than relying solely on raw power. This guide details how to obtain and build the Pathocyst, including a powerful endgame build.

Glaive enthusiasts seeking a change of pace will find the Pathocyst a compelling option. The Technocyst Coda variant significantly boosts damage, making it viable for challenging Steel Path content.

Acquiring the Pathocyst

The Pathocyst is a craftable melee weapon. Defeat the Zealoid Prelate boss on Exequias, Deimos, to obtain its blueprint (and potentially component blueprints). Gather the necessary resources and craft the weapon.

To acquire the damage-enhanced Coda Pathocyst, complete "The Hex" quest, unlock the Hollvania hub, and farm Live Heartcells. Trade these with Eleanor in Hollvania; the Coda Pathocyst is part of her rotating inventory (Rotation B). Check back periodically if it's unavailable.

Pathocyst Crafting Requirements
Pathocyst Blueprint	2 Pathocyst Blades
Pathocyst Handle	5 Neurodes
Credit Cost: 30,000 Credits	Crafting Time: 24 Hours

Pathocyst Stats and Abilities

Base Damage
	Pathocyst	Coda Pathocyst
Impact	57	58
Puncture	55	55
Slash	61	65
Viral	89	92
Total	262	270
Other Damage Stats
Attack Speed	0.667	0.667
Critical Chance	15%	20%
Critical Multiplier	2.1x	2.3x
Status Chance	30%	35%
Misc.
Weapon Type	Glaive
Follow Through	70%
Range	1.3m
MR Requirement	MR 9	MR 17

The Pathocyst's unique feature is its maggot swarm. Each attack releases maggots that latch onto and stun enemies, providing valuable crowd control. While not high-damage dealers, the maggots significantly aid in battlefield management. Despite lower base stats than the Glaive Prime, its critical stats and damage make it a strong contender for heavy attack builds. The slow attack speed, however, warrants consideration of attack speed mods for melee combat.

Pathocyst Build Recommendations

This guide focuses on a heavy attack build maximizing status damage via critical stats, Galvanized mods, and the Melee Influence Arcane for exceptional DPS. Prioritizing the Coda Pathocyst is highly recommended.

Endgame Build

(Note: Overframe's mod availability may vary at the time of reading. The build below assumes access to Galvanized Reflex and Galvanized Elementalist.)

Forma	3 (3V)
Variant	Coda Pathocyst

This build prioritizes the Pathocyst's heavy attack. Melee Influence is key, spreading status procs (ideally Electricity, triggered by Focus Energy). Blast damage (Vicious Frost Volcanic Edge) synergizes well with Melee Influence. Galvanized Elementalist scales Blast damage, Galvanized Reflex boosts heavy attack efficiency and combo multiplier, and Primed Pressure Point enhances base damage. Sacrificial Steel and Amalgam Organ Shatter further improve critical stats. This results in a high-damage Glaive capable of clearing large enemy groups when Melee Influence activates. If Electricity procs are infrequent, consider Weeping Wounds instead of Galvanized Reflex to increase status chance.

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